Safety of Therapeutic Fever Induction in Cancer Patients Using Approved PAMP Drugs

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Safety of Therapeutic Fever Induction in Cancer Patients Using Approved PAMP Drugs

William Coley, between 1895 and 1936, treated hundreds of cancer patients using infusions of fever inducing bacerial extracts. Similar experiments were done by Klyuyeva and co-workers in the 1940ies in Russia using trypanosoma extracts. Many remissions and cures were reported. We have conjectured that pathogen associated molecular pattern substances (PAMP) are the molecular explanation for the ...

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ژورنال

عنوان ژورنال: Translational Oncology

سال: 2018

ISSN: 1936-5233

DOI: 10.1016/j.tranon.2018.01.019